Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Tocris Bioscience™ VUF 11222
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High affinity non-peptide CXCR3 agonist
| Target | Chemokine Receptor Agonists |
|---|---|
| CAS | 1414376-84-3 |
| Purity | >98% |
| Chemical Name or Material | 2′-Bromo-N-[[(1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl]methyl]-N,N-dimethyl-[1,1′-biphenyl]-4-methanaminium iodide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C25H31BrIN |
| Formula Weight | 552.33 |
Tocris Bioscience™ SCH 442416
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CAS: 316173-57-6 Molecular Formula: C20H19N7O2
| CAS | 316173-57-6 |
|---|---|
| Molecular Formula | C20H19N7O2 |
Tocris Bioscience™ N-Acetylpuromycin
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Downregulates SnoN and Ski protein expression; promotes TGF-β signaling
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Tocris Bioscience™ IP7e
Tocris Bioscience™ IP7e
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Potent Nurr1 activator
| Target | NFkB/IkB Inhibitors |
|---|---|
| CAS | 500164-74-9 |
| Purity | >98% |
| Chemical Name or Material | 6-[4-[(2-Methoxyethoxy)methyl]phenyl]-5-methyl-3-phenyl-isoxazolo[4,5-c]pyridin-4(5H)-one |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C23H22N2O4 |
| Formula Weight | 390.43 |
Tocris Bioscience™ Ropinirole
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CAS: 91374-20-8 Molecular Formula: C16H25ClN2O
| CAS | 91374-20-8 |
|---|---|
| Molecular Formula | C16H25ClN2O |
Tocris Bioscience™ LY 404187
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Selective AMPA receptor positive allosteric modulator
| Target | AMPA Receptor Modulators |
|---|---|
| CAS | 211311-95-4 |
| Purity | >98% |
| Chemical Name or Material | N-[2-(4′-Cyano[1,1′-biphenyl]-4-yl)propyl]-2-propanesulfonamide |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C19H22N2O2S |
| Formula Weight | 342.46 |
Tocris Bioscience™ Kenpaullone
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CAS: 142273-20-9 Molecular Formula: C16H11BrN2O
| CAS | 142273-20-9 |
|---|---|
| Molecular Formula | C16H11BrN2O |
Tocris Bioscience™ TCS ERK 11e
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CAS: 896720-20-0 Molecular Formula: C24H20Cl2FN5O2
| CAS | 896720-20-0 |
|---|---|
| Molecular Formula | C24H20Cl2FN5O2 |
Tocris Bioscience™ Zatebradine hydrochloride
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CAS: 91940-87-3 Molecular Formula: C26H37ClN2O5
| CAS | 91940-87-3 |
|---|---|
| Molecular Formula | C26H37ClN2O5 |
Tocris Bioscience™ Sivelestat sodium salt
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CAS: 150374-95-1 Molecular Formula: C20H21N2NaO7S
| CAS | 150374-95-1 |
|---|---|
| Molecular Formula | C20H21N2NaO7S |
Tocris Bioscience™ JNJ 28871063 hydrochloride
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CAS: 944342-90-9 Molecular Formula: C24H28Cl2N6O3
| CAS | 944342-90-9 |
|---|---|
| Molecular Formula | C24H28Cl2N6O3 |
Tocris Bioscience™ Thalidomide 4'-oxyacetamide-alkylC1-PEG3-alkylC3-amine
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Cereblon ligand with alkyl-PEG-alkyl linker and terminal amine for onward chemistry
Tocris Bioscience™ TCH-165
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Enhancer of 20S proteasome assembly and 20S-mediated protein degradation
| Target | Proteasome Modulators |
|---|---|
| CAS | 1446350-60-2 |
| Purity | 0.98 |
| Chemical Name or Material | Ethyl (4 R,5 R)-rel-1-benzyl-5-(4-(benzylamino)phenyl)-2-(4-methoxyphenyl)-4-phenyl-4,5-dihydro-1 H-imidazole-4-carboxylate |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C39H37N3O3 |
Tocris Bioscience™ ADX 10059 hydrochloride
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CAS: 757949-98-7 Molecular Formula: C15H14ClFN2
| CAS | 757949-98-7 |
|---|---|
| Molecular Formula | C15H14ClFN2 |
Tocris Bioscience™ SIS17
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Selective HDAC11 inhibitor
| Target | HDAC11 |
|---|---|
| CAS | 2374313-54-7 |
| Purity | 0.95 |
| Chemical Name or Material | N'-Hexadecylthiophene-2-carbohydrazide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H38N2OS |